Overview
What is MeltSim?
MeltSim : The DNA Melting Simulator
In depth
A closer look at MeltSim
MeltSim is a statistical-mechanical program for calculating melting (denaturation) curves (derivative profiles) and maps of DNA, from genes to genomes. The model is the one-dimensional Ising lattice to which loop entropy has been appended. The original algorithm is that of Poland & Scheraga and Poland, with the Fixman & Friere approximation of the loop entropy by a sum of exponentials. Parameters in Poland's original algorithm were evaluated by Blake & Delcourt and provide near-quantitative agreement between observed and calculated Tm, amplitudes, breadths, and areas of transitions obtained under equilibrium conditions. The program stores the results of the operation in a log file that allows you to review important information and operations.
Verdict
Should you download MeltSim?
MeltSim runs on
Windows 10/11
and is available under the
GNU Public License
license
— the installer is 510 KB.
We’ve catalogued it under
Science and Engineering.
✓
Verified clean. Every MeltSim build on SoftLookup is scanned for viruses, spyware, adware, trojans and backdoors. We re-test on every update.
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At a glance
MeltSim specifications
- Publisher
-
MeltSim Team
- Last updated
- Oct 11, 2023
- License
- GNU Public License
- Operating system
- Windows 10/11
- File size
- 510 KB
- Price
- Free
- Page views
- 546
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