Windows · Free download · Science and Engineering

MeltSim1.0

MeltSim : The DNA Melting Simulator

Operating system
Windows 10/11
File size
510 KB
License
GNU Public License
Last updated
Oct 11, 2023

62 downloads·546 page views

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Overview

What is MeltSim?

MeltSim : The DNA Melting Simulator

In depth

A closer look at MeltSim

MeltSim is a statistical-mechanical program for calculating melting (denaturation) curves (derivative profiles) and maps of DNA, from genes to genomes. The model is the one-dimensional Ising lattice to which loop entropy has been appended. The original algorithm is that of Poland & Scheraga and Poland, with the Fixman & Friere approximation of the loop entropy by a sum of exponentials. Parameters in Poland's original algorithm were evaluated by Blake & Delcourt and provide near-quantitative agreement between observed and calculated Tm, amplitudes, breadths, and areas of transitions obtained under equilibrium conditions. The program stores the results of the operation in a log file that allows you to review important information and operations.

Verdict

Should you download MeltSim?

MeltSim runs on Windows 10/11 and is available under the GNU Public License license — the installer is 510 KB. We’ve catalogued it under Science and Engineering.

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At a glance

MeltSim specifications

Publisher
MeltSim Team
Last updated
Oct 11, 2023
License
GNU Public License
Operating system
Windows 10/11
File size
510 KB
Price
Free
Page views
546

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